April 26, 1834 born in the village Tatarivschyna, nearby Oster, Chernihiv region.
1853 graduated from the 2nd Kyiv Gymnasium.
October 9, 1853 entered the Medical Faculty of Kyiv St. Volodymyr University.
1860 graduated with honors from Medical Faculty of Kyiv St. Volodymyr University.
From May 1861 to September 1862 traveled to Vienna and other European cities, where worked in laboratories of prominent scientists: Brucke, Ludwig (Vienna) and Bunsen (Heidelberg); he also attended lectures by Kolliker (Wurzburg), Kirchhoff and Helmholtz (Heidelberg).
In the early 1860s Betz concentrated more and more attention on the study of the brain.
1863, in Kyiv defended his thesis "On the mechanism of the blood circulation in the liver".
1863 by the contest was appointed as the anatomy coroner at the Medical Faculty of Kyiv St. Volodymyr University.
From 1864 to 1867 taught anatomy to students who studied Natural Sciences and histology at the Medical Faculty of Kyiv St. Volodymyr University.
Since 1865 began his work on the anatomy of the central nervous system and its microscopic structure.
1868 confirmed as extraordinary professor in the Department of Anatomy at Kyiv St. Volodymyr University.
1870 confirmed as full professor in the Department of Anatomy at Kyiv St. Volodymyr University in the rank of state councilor.
1870 unique preparations made by Volodymyr Betz demonstrated at the All-russian manufacture exhibition in St. Petersburg, where they awarded a large silver medal.
December 25, 1870 awarded the St. Stanislaus Order of 2nd degree with the Imperial Crown.
Since 1871 appointed as a consultant on nervous diseases at the Hospital of St. Cyril in Kyiv, and later - at the main hospital of South Western Railway.
In 1872 at the congress of scientists and doctors in Leipzig, V. Betz impressed his European colleagues with his collection of histological preparations.
In 1872 at his own expense opened a photoengraving studio at the anatomical theater in the Kyiv St. Volodymyr University.
In 1873, at the Worldwide Exhibition in Vienna, V. Betz awarded the «Fortschritts Medaille» ("Medal of Success"), and Professor Benedict offered to buy his histological collection for 7000 guilders, but Betz refused.
December 23, 1873 awarded the St. Anne Order of 2nd degree.
1874 discovered and described the giant pyramidal neurons in the fifth layer of the primary motor cortex which later were named Betz cells.
1883 together with historian Volodymyr Antonovych published on own expense the book "Historical figures of South-Western Russ", containing essays about famous Ukrainian personalities, including the hetmans Sagaydachnyi and Khmelnytskyi.
Since 1884 held the post of the chief physician of South Western Railway.
1887 published a monograph "Bone Morphology", resulting the great work on his collection of bones and skulls that had no equal in the whole Europe.
1890 at his own expence published (unfortunately, only in one copy) "Atlas of the Human Brain", which contained pictures of macroscopic preparations of the human brain and brains of various animal species.
1890 The end of the regular term of V. Betz as Head of the Department of Anatomy Kyiv St. Volodymyr University. Through the pressure of University administration, Betz decided not to apply for a competition for one more term as Head of the Department of Anatomy at Kyiv St. Volodymyr University. Under the pretext of a heart disease, V. Betz submitted resignation and finished his work at the University.
October 12, 1894 Volodymyr Betz died.
After his testament, he was buried on the territory of Vydubytski monastery in Kyiv.